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MOTS-c: Overview of Preclinical Research and Mechanistic Insights
Introduction MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a mitochondria-derived peptide that has gained increasing attention in the field of metabolic and mitochondrial research. Unlike many signalling molecules encoded by nuclear DNA, MOTS-c is encoded within mitochondrial DNA, placing it within a unique category of peptides involved in cellular energy regulation. Scientific
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SS-31 (Elamipretide): Overview of Preclinical and Clinical Research
Introduction SS-31, also known as Elamipretide, is a mitochondria-targeting peptide that has been the subject of increasing scientific interest in both preclinical and clinical research settings. Unlike many compounds studied primarily at the cellular level, SS-31 has progressed into human trials, particularly in the context of mitochondrial-related disorders. Research into SS-31 focuses on its interaction